Scope and policy of the Journal

Biomedical Papers publishes reviews and original articles reporting on basic and clinical research in medicine. Articles in BIOMEDICAL PAPERS are published in English. Manuscripts are reviewed by independent reviewers selected by the Editors. First they are subjected to a preliminary peer review process to determine their suitability for publication, provided they fulfill the requirements of the journal as laid out in the instructions to authors. After the review, manuscripts are returned for revision along with the reviewer’s and/or editor’s comments within 30 days.

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COPYRIGHT NOTICE

Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0) that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
Open Access Statement
This is an open access journal which means that all content is freely available without charge to the user or his/her institution. Users are allowed to read, download, copy, distribute, print, search, or link to the full texts of the articles, or use them for any other lawful purpose, without asking prior permission from the publisher or the author.

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Submission of manuscripts

Manuscripts must be submitted exclusively online at: http://biomed.papers.upol.cz. Submission of an article implies that the work described has not been published previously (except in the form of an abstract or as part of a published lecture or academic thesis), that it is not under consideration for publication elsewhere, that publication is approved by all authors (the manuscript has been read and approved by all named authors and that there are no other persons who satisfied the criteria for authorship but are not listed) and tacitly or explicitly by the responsible authorities where the work was carried out, and that, if accepted, it will not be published elsewhere in the same form, in English or in any other language, including electronically without the written consent of the copyright-holder.

iThenticate plagiarism detection: All manuscripts submitted to Biomedical Papers (editorial system Actavia) are checked using the IThenticate software. This provides us with a similarity report listing (a) the percentage of similarities resulting from counted words and (b) the markup of the various sections, expressions, or terms which were found in other documents.

Conflict of interest: At the end of the text, under a subheading "Conflict of Interest Statement" all authors must disclose any financial or personal relationships with other people or organizations within 3 years of beginning the work submitted that could inappropriately influence the work submitted. Examples of conflicts include employment, consultancies, stock ownership, honoraria, paid expert testimony, patent applications/registrations, and grants. If there are no conflicts of interest, the authors should state that there are none. Investigators should disclose potential conflicts to participants in clinical trials and other studies and should state in the manuscript whether they have done so. If you have no declaration to make, please write: None declared.

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Preparation of manuscript

Language:
Manuscripts should be written in good and clear English. Please have your text proofread by a native English speaker before you submit it for consideration.

Cover letter:
Each manuscript should be accompanied by a cover letter containing a short statement by the authors describing the novelty and importance of their research. All cover letters are required to include the statements:

  • We confirm that neither the manuscript nor any parts of its content are currently under consideration or published in another journal.
  • All authors have approved the manuscript and agree with its submission to Biomedical Papers.

Reviewers:
The authors should provide 2-3 potential reviewers. Kindly provide reviewers‘ full names, addresses and e-mail addresses.

Brief summary:
Include with your MS short text (500-750 characters – not words) with focus on originality, key findings, significance and without repeating title terms. A short summary of your manuscript is what will interest our readers.

Graphical Abstract:
Graphical Abstracts are required for Original research articles and Review articles. A Graphical Abstract is a visual representation or summary of the main findings or key points of a research paper. This should allow readers to quickly grasp the essential content and main conclusions before reading the article. Please see the end of Instruction to Authors for more detailed instructions.

Manuscript organization:
Type the manuscript (including table and figure legends) using 1,5 spacing Times New Roman font size of 12. Do not submit your manuscript in PDF format.
The abstract and text pages should have consecutive line numbers in the left margin beginning in the abstract and ending before the reference section. Number pages consecutively of each page, beginning with the title page.
Manuscripts that do not respect the requirements of the Journal, as specified under 'Instructions to Authors', will be rejected outright.
When you submit your work, please ensure the following:

  • The manuscript is complete and uploaded correctly.
  • The full names of all authors are provided (first name and family name).
  • Authors’ affiliations are complete, include the name and e-mail of the corresponding author, written in italics.
  • All Figures and Tables have been uploaded and appear correctly.
  • Graphical Abstract, Abstract, Key words, List of Abbreviations (if necessary), Tables and Figures are included.
  • References are in the correct format and cited sequentially in the text.
  • Ethical approval has been obtained and mentioned in the text, if applicable.
  • Registration of Clinical Trials.
  • Author contributions are included.
  • Authors’ conflict of interest declaration is included.
  • A cover letter containing a brief statement highlighting the value and significance of the work.
  • SI units are used. (abbreviations of units)
  • Numbers have decimal points, no commas, also in Tables and Figures.

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Manuscript organization

(See: EXAMPLE OF MS FORMATTING AND STYLE REQUIREMENTS)
The manuscript should be divided into: Title page (title, authors’ names, affiliations), Graphical Abstract, structured Abstract, and main text. The text generally should be as follows: Introduction, Materials and Methods, Results and Discussion, Conclusion, Acknowledgements and References. In the case of Short communications, sections may be combined, e.g. Materials and Methods and Results or Results and Discussion. Short Communications should be no more than 8 typed pages (1,5 line spacing) including tables and figures. For abstracting purposes, up to eight key words should be added below the Abstract.

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GRAPHICAL ABSTRACT

Graphical Abstracts are required for Original research articles and Review articles. A Graphical Abstract is a visual representation or summary of the main findings or key points of a research paper. This should allow readers to quickly grasp the essential content and main conclusions before reading the article. Authors must use one of the Graphical Abstract Templates provided at the end of Instruction to Authors. Please see the end of Instruction to Authors for more detailed instructions.

Abstract

The structured abstract not exceeding 250 words, should contain: (i) Aims (a clear statement of the objectives of the paper), (ii) Methods (a brief description of the methods you used including study design, if appropriate), (iii) Results (a concise summary of results, numerical and statistical data results if applicable appropriate and in close relationship to the Aims of the paper), (iv) Conclusion (provide only conclusions of the study that are directly supported by the results, avoid speculation and indicate whether additional study is required for using the results in routine clinical settings if this applies.

Reviews
The abstract of a review and some notes in general on review writing are under Appendix to "Instructions to Authors". http://biomed.papers.upol.cz).

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Tables

Authors are asked to keep tabular matter to a minimum (max. 4). Tables should have a title above and an explanatory footnote below. Each line and column should be titled. The same data should not be reproduced in both tables and figures. Tables and illustrations should be completely intelligible without referring to the text. Refer to Tables in the text as Table 1.

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Figures

Please keep the numbers of figures to a minimum (max. 4). Provide a short descriptive title and a legend, below the Figure. All figures and photographs should be suitable for black and white reproduction. Please note it is the author´s responsibility to obtain copyright permission to reproduce figures. Refer to Figures in the text as Fig.1.

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Nomenclature and abbreviations

Where possible, nomenclature, and abbreviations should be in accord with internationally agreed rules. Official names of drugs are preferred to trade names. If trade names are used, they should be capitalized and the trade mark included.
It is necessary that the abbreviations used in the main text should be defined at the end of the article. Abbreviations used in the Abstract must be defined within the Abstract.

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Acknowledgements

Acknowledgements and details of non-financial support must be included at the end of the text before References. Please note that declarations regarding conflicts of interest should be given separately.

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AUTHOR CONTRIBUTIONS

This information must be included in your manuscript.

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Conflict of interest statement

This information must be included in your manuscript before the References in this format:
CONFLICT OF INTEREST STATEMENT:
The authors state that there are no conflicts of interest regarding the publication of this article.
If you have no declaration to make, please write: None declared.

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Use of animals in experimental studies

All studies involving the use of animals must contain language and, if necessary, support documentation indicating that the studies were conducted in accordance with the laws and regulations of governing authorities. A clear statement regarding approval by the local Institutional Animal Care and Use Committee (IACUC) or equivalent must be made in the Methods Section.

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Use of humans, human tissues, and clinical trials

All studies involving humans or human tissues must be approved by the appropriate Institutional Ethical Committee (IEC) in accordance with laws and policies of governing authorities. A clear statement regarding the use of humans in studies and the source of human tissues must be made in the Methods Section with appropriate references to Informed Consent and Research Protection, if required by the ICE. Support documentation may also be request by the journal or its editorial board.

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Registration of Clinical Trials

Biomedical Papers requires, as a condition for consideration for publication, registration of all clinical trials in a public trials registry at or before the time of first patient enrollment. A clinical trial is any study that prospectively assigns human subjects to intervention or comparison groups to evaluate the cause and effect relationship between a medical/surgical intervention and a health outcome. As recommended by the International Committee of Medical Journal Editors (ICMJE), Biomedical Papers accepts registration in any registry that is a primary register of the WHO International Clinical Trials Registry Platform (ICTRP) or in ClinicalTrials.gov, which is a data provider to the WHO ICTRP. Trial registry name, registration identification number, and the URL for the registry should be included at the end of abstract. Manuscripts reporting the results of randomized controlled trials should include the CONSORT flow diagram showing the progress of patients throughout the trial. The CONSORT checklist also should be completed and submitted with the manuscript and can be found on http://www.consort-statement.org/consort-statement.

References

Adhere strictly to the reference style of the Journal. All references mentioned in the numbered list at the end of the papers, must be mentioned in the text, and vice versa. List and number the references consecutively in the order that they appear in the text, including Tables and Figures. In the text, identify references by using superscript Arabic numerals: 1, 2. References in the text after brackets, abbreviation, units, numbers write: (ref.1).
Full references in the numbered list should contain the names of all authors (identify authors by last name first, followed by up to 2 initials, without full stop), full title of the paper, the abbreviated journal title (without full stop). After the abbreviated journal name give the year of publication, followed by a semicolon, the volume number (issue number), followed by a double colon and the page numbers, with the last page number in shortened format. Formatting samples are given below:

Articles in journals
1. Reiter R, Burk RF. Effect of oxygen tension on the generation of alkanes and malondialdehyde by peroxidizing rat liver microsomes. Biochem Pharmacol 1978;36(5):925-9.

Articles ahead of print
2. Leve F, Morgado-Díaz JA. Rho GTPase signaling in the development of colorectal cancer. J Cell Biochem 2012 Mar 30.[Epub ahead of print] doi:10.1002/jcb.24153

Book
3. Winer BJ. Statistical principles in experimental design. New York: McGraw-Hill; 1971.
4. Gilstrap LC, Cunningham FG, VanDorsten JP, editors. Operative obstetrics. 2nd ed. New York: McGraw Hill; 2002.

Chapter in a book
5. Shatkin AJ. Colorimetric reactions for DNA, RNA, and protein determinations. In: Habel K, Salzman NP, editors. Fundamental techniques in virology. New York: Academic Press; 1969. p. 231-237.

Conference paper
6. Wefers H, Sies H. Generation of photoemissive species during quinone redox cycling. In: Alexander P, editor. Bioreduction in the Activation of Drugs. Proceedings of the Second Biochemical Pharmacology Symposium; 1985 25-26 July; Oxford, UK. Oxford: Pergamon Press; 1986. p. 26-34.

Journal article on the internet
7. Abood S. Quality improvement initiative in nursing homes: the ANA acts in an advisory role. Am J Nurs [serial on the Internet]. 2002 Jun [cited 2002 Aug 12]; 102(6):[about 3 p.]. Available from: http://www.nursingworld.org/AJN/2002/june/Wawatch.htm

References of internet source Author (the person or organisation responsible for the site), title, year (date created or last updated), URL, accessed month day year (you viewed the site)
8. National Comprehensive Cancer Network. Small Cell Lung Cancer (Version 2.2024). Available from: https://www.nccn.org/professionals/physician_gls/pdf/sclc.pdf. [accessed Nov 10, 2023]
9.Gondi V, Tome WA, Rowley HA, Mehta MP. Hippocampal contouring: A Contouring Atlas for RTOG 0933. (2021) Available from: https://www.nrgoncology.org/ciro-brain [accessed Jan 15, 2024]
10. Longy M. PTEN (Phosphatase and Tensin homolog deleted on chromosome Ten). (1999) Available from: http://atlasgeneticsoncology.org/Genes/PTENID158.html [accessed Oct 27, 2021]

The titles of journals should be abbreviated in accordance with Index Medicus.

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Footnotes

Symbols indicating author affiliation should be superscript number: 1, 2, 3,.

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FEE NOTIFICATION

The fee of 13.000 Czech crowns or 600 EUR (plus VAT or local taxes where applicable) will apply to all manuscripts accepted for publication. Accepted manuscripts will not proceed further without receipt of payment.

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Rejection of manuscripts

Manuscripts dealing with topics that have been well-studied in the literature, and that do not resolve questions raised by previous studies, or manuscripts that are statistically underpowered, are likely to be rejected without peer review.

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Appendix to „Instructions to Authors“ for Review articles

Reviews for Biomedical Papers should provide a valuable evaluation of the literature in a particular area or subject and propose future directions. They should be easily understood by the general readership of the journal. A good review is a critical judgement of different studies, especially where there are conflicting data. It is not a simple summary or even repetition of published review articles.

Authorship
No more than 5 authors are preferred.

Abstract

  • 250 words, briefly explain the necessary background in a short one or two sentences and encapsulate the take-home message for a non-specialist reader in the conclusion.
  • Please emphasize recent developments, novel conclusions, concepts and models that make your review timely and relevant.

Keywords
Please provide 4-6 descriptive keywords.

Search strategy and selection criteria
Transparency about the choice of material included is important to any Review paper. Therefore, the Review should include a brief section entitled "Search strategy and selection criteria" after the CONCLUSION stating the sources of the material covered, and the criteria used to include or exclude studies. Citations to papers published in non-peer-reviewed supplements are discouraged.

Example of Search strategy and selection criteria:
Our research strategy was aimed at evaluating studies on the role of the transcription factors (Nrf2 and NF-κB) in skin restoration to determine if they can be used as markers. Scientific articles from 1974 to 2016 were searched using the PubMed and Web of Science databases. All searches were up to date as of August 2016. The search terms used included “skin wound healing”, “models for wound healing”, “evaluation of wound healing”, “Nrf2 in wound healing”, “NF-κB in wound healing” and “interconnection between Nrf2 and NF-κB”. Only English language papers were reviewed.
(Source: Ambrozova N, Ulrichova J, Galandakova A. Models for the study of skin wound healing. The role of Nrf2 and NF-κB. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2017 Jan 6. doi: 10.5507/bp.2016.063. [Epub ahead of print])

References

  • No more than 100 references.
  • Citations and reference format should be in MEDLINE referencing style.

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Graphical Abstract

Graphical abstracts are required for original research articles and review articles. This image will be published with the article on the Journal website. It is the responsibility of all authors to create their own graphical abstract.

Authors must use one of the Graphical Abstract templates provided below when preparing their graphical abstract, and should submit their graphical abstract as a PowerPoint file. As a self-explanatory piece, a Graphical Abstract should allow readers to understand the essential content before reading the article.

General considerations

A graphical abstract is a single, pictorial and visual summary of the main findings of the scientific article. While preparing a graphical abstract, please consider that it is aimed at:

  • allowing readers, the vast majority of which are not experts in the field, to quickly gain an understanding of the take-home message of the paper;
  • helping readers identify more quickly which papers are most relevant to their research interests;
  • enhancing research dissemination through social media, e.g., X, Facebook, Instagram, LinkedIn.

The ideal graphical abstract should be simple and self-explanatory, with a mix of text (used sparingly) and images. The graphical abstract of a research paper should include the following components:

  • a descriptive title that defines the subject with plain language and does not anticipate the conclusion;
  • a section highlighting the context of the research (background, aim);
  • where reasonable and important to convey the manuscript’s impact, a section briefly summarizing the methodology employed;
  • a section reporting the main outcomes;
  • 1-2 conclusions (key points);
  • Authors and DOI placeholder. DOI will be added later by editorial staff.

Graphical Abstract Preparation

Graphical abstracts must be original; material reproduced from other sources may not be used. In preparing graphical abstracts, authors should only use images for which they have permission or rights. To avoid any potential problems, either use the copyright filter during an image search online or subscribe to an icon image bank. The internet has many image banks which are free to use, and copyright images are prohibited from use.

Additional assistance:

  • Lettering must be large enough to be legible (Font Arial 11 to 20 points – see instructions in the templates)
  • Select bold, solid color icons
  • Avoid highly detailed icons as the intricacy may be lost in the small format
  • Exclude trade names, logos, or images of trademarked items
  • Keep the use of text to a minimum, and avoid presenting data in tabular form
  • If the image depicts a biological or biochemical process, it should flow from left to right or top to bottom
  • Avoid excessive detail, overcrowded presentation, or clutter.

Templates for Creating a Graphical Abstract in PowerPoint

Authors must use one of the Graphical Abstract Templates provided below when preparing their graphical abstract.

Templates:

Biomedical Papers Templates for the graphical abstract is available here or below among the attached files.

Supplementary files

Download fileBP_VA2.pptx

File size: 94.35 kB