Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2007, 151(2):267-271 | DOI: 10.5507/bp.2007.045

Evaluation of transcutaneous bilirubinometry in preterm infants of gestational age 32-34 weeks

Lucia Stillovaa, Katarina Matasovaa, Tatiana Mikitovaa, Juraj Stillab, Hana Kolarovszkaa, Mirko Zibolena
a Clinic of Neonatology, Jessenius Faculty of Medicine, Comenius University, Faculty Hospital of Martin, Martin, Slovakia
b Clinic of Stomatology and Maxillofacial Surgery, Jessenius Faculty of Medicine, Comenius University, Faculty Hospital of Martin, Martin, Slovakia

Aims: The aim of this prospective study was to evaluate the accuracy of transcutaneous bilirubinometry using the Minolta Air-Shields JM-103 device in preterm newborns of gestational age 32-34 weeks, and to identify the most appropriate measurement site.

Methods: Transcutaneous bilirubin (TcB) measurements were performed over forehead, sternum and abdomen, if total serum bilirubin (TSB) had to be determined on clinical indication in neonates of selected gestational age. TSB levels were measured in a clinical laboratory using direct spectrophotometry. In order to assess transcutaneous bilirubinometry accuracy, differences between TSB and TcB, their CI95%, and correlation coefficients (r) between TcB and TSB were evaluated.

Results: The study group consisted of 44 infants, including 6 very low birth weight (VLBW) neonates. The correlations between transcutaneous and laboratory values were found to be significant and close. Minimal differences were observed when measured over sternum. The measurements over forehead had a tendency to underestimate TSB levels.

Conclusions: Noninvasive measurement by Minolta JM-103 demonstrated significant accuracy. The authors recommend measurements over sternum or abdomen in premature infants born within 32-34 gestational weeks as a reliable and accurate neonatal hyperbilirubinemia screening test. Transcutaneous bilirubinometry has the potential to reduce the number of blood samplings, thus reducing neonatal pain and discomfort, parental distress and medical care cost.

Keywords: Bilirubin, Minolta JM-103, Neonatal jaundice, Preterm infants

Received: August 31, 2007; Accepted: September 28, 2007; Published: December 1, 2007  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Stillova, L., Matasova, K., Mikitova, T., Stilla, J., Kolarovszka, H., & Zibolen, M. (2007). Evaluation of transcutaneous bilirubinometry in preterm infants of gestational age 32-34 weeks. Biomedical papers, 151(2), 267-271. doi: 10.5507/bp.2007.045
Share...
Download citation
  • BibTeX (.bib)
  • Bookends (.ris)
  • EasyBib (.ris)
  • EndNote (.enw)
  • EndNote 8 (.xml)
  • ISI WoS (.isi)
  • Medlars (.medlars)
  • Mendeley (.ris)
  • MODS (.xml)
  • Papers (.ris)
  • RefWorks (.txt)
  • RefManager (.ris)
  • RIS (.ris)
  • MS Word (.xml)
  • Zotero (.ris)
    • Open full article

    References

    1. Subcommittee on hyperbilirubinemia. Management of hyperbilirubinemia in the newborn infant 35 or more weeks of gestation. Pediatrics 2004; 114(1):297316. Go to original source... Go to PubMed...
    2. Ip S, Chung M, Kulig J, OBrien R, Sege R, Glicken S, Maisels MJ, Lau J, Subcommittee in hyperbilirubinemia. An evidence-based review of important issues concerning neonatal hyperbilirubinemia. Pediatrics 2004; 114(1):130153. Go to original source... Go to PubMed...
    3. Yasuda S, Itoh S, Isobe K, Yonetani M, Nakamura H, Nakamura M, Yamauchi Y, Yamanishi A. New transcutaneous jaundice device with two optical paths. J Perinat Med 2003; 31:8188. Go to original source... Go to PubMed...
    4. Matasova K, Zibolen M, Ciljak M, Kolarovszka H, Murgas D, Baska T. Spolahlivost neinvazivneho merania koncentracie bilirubinu u zdravych novorodencov. Ces.-slov. Pediat. 2005; 60:599605.
    5. Sanpavat S, Nuchprayoon I. Noninvasive Transcutaneous Bilirubin as a Screening Test to Identify the Need for Serum Bilirubin Assessment. J Med Assoc Thai 2004; 87:11931198.
    6. Barko HA, Jackson GL, Engle WD: Evaluation of a point-of-care direct spectrophotometric method for measurement of total serum bilirubin in term and near-term neonates. Journal of Perinatology 2006; 26:100105. Go to original source... Go to PubMed...
    7. Maisels MJ, Ostrea EM, Touch S, Clune SE, Cepeda E, Kring E, Gracey K, Jackson C, Talbot D, Huang R. Evaluation of a New Transcutaneous Bilirubinometer. Pediatrics 2004; 113:1628 1635. Go to original source... Go to PubMed...
    8. Ho HT, Ng TK, Tsui KC, Lo YC. Evaluation of a new transcutaneous bilirubinometer in Chinese newborns. Archives of Disease in Childhood Fetal and Neonatal Edition 2006; 91:F434-F438. Go to original source... Go to PubMed...
    9. Engle WD, Jackson GL, Stehel EK, Sendelbach DM, Manning MD. Evaluation of a transcutaneous jaundice meter following hospital discharge in term and near-term neonates. J Perinatol. 2005; 25(7):48690. Go to original source... Go to PubMed...
    10. Yamanishi A, Yamauchi Y, Kabe K, Ino M. New transcutaneous bilirubin measurement unit with two optical paths. Acta Neonat Jpn 2001; 37:415.
    11. Bystricka A, Bauer F. Iktery u extremne nezrelych novorodencov. In: Demova K., Bystricka A., Bauer F. Pokroky v neonatologii 1- Extremne nezrely novorodenec. Vydavatelstvo NNSP; 2006. p. 4560.
    12. Namba F, Kitajima H. Utility of a new transcutaneous jaundice device with two optical paths in premature infants. Pediatrics International 2007; 49:497501. Go to original source... Go to PubMed...
    13. Nanjundaswamy S, Petrova A, Mehta R, Bernstein W, Hegyi T. The accuracy of transcutaneous bilirubin measurements in neonates: a correlation study. Biol Neonate 2004; 85:2125. Go to original source... Go to PubMed...
    14. Willems WA, van den Berg LM, de Wit H, Molendijk A. Transcutaneous bilirubinometry with the Bilicheck in very premature newborns. Journal of Maternal-Fetal and Neonatal Medicine 2004; 16:209214. Go to original source... Go to PubMed...
    15. Eyw H, Syr L, Cb C, Jwy C. BiliCheck transcutaneous bilirubinometer: a screening tool for neonatal jaundice in the Chinese population. Hong Kong Med J 2006; 12 (2):99102.
    16. Rubaltelli FF, Gourley GR, Loskamp N, Modi N, Roth- Kleiner M, Sender A, Vert P. Transcutaneous bilirubin measurement: a multicenter evaluation of a new device. Pediatrics 2001; 107(6):1264 1271. Go to original source... Go to PubMed...
    17. Knupfer M, Pulzer F, Braun L, Heilmann A, Robel-Tillig E, Vogtmann C. Transcutaneous bilirubinometry in preterm infants. Acta Paediatr 2001; 90:899903. Go to original source... Go to PubMed...
    18. Jangaard KA, Curtis H, Goldbloom RB. Estimation of bilirubin using BiliChek, a transcutaneous bilirubin measurement device: Eff ects of gestational age and use of phototherapy. Paediatr Child Health 2006; 11:7983. Go to original source...
    19. Mercanti I, Michel F, Thomachot L, Loundou DA, Nicaise C, Vialet R, DiMarco JN, Lagier P, Martin C. Transcutaneous bilirubin measurement in preterm infants. Archives de Pediatrie 2007; 14(7):875880. Go to original source... Go to PubMed...
    20. Karolyi L, Pohlandt F, Muche R, Franz AR, Mihatsch WA. Transcutaneous bilirubinometry in very low birthweight infants. Acta Paediatrica 2004; 93:941944. Go to original source... Go to PubMed...
    21. Sanpavat S, Nuchprayoon I. Comparison of two transcutaneous bilirubinometers- Minolta AirShields Jaundice Meter JM103 and Spectrx Bilicheck in Thai neonates. Southeast Asian J Trop Med Public Health 2005; 36:15337
    22. Rennie JM, Roberton NRC. Neonatal Jaundice and Liver Disease. In: Rennie JM, Roberton NRC. A Manual of Neonatal Intensive Care. 4. vyd. London: Arnold; 2002. 417418.

    Return to the content