Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2018, 162(4):258-262 | DOI: 10.5507/bp.2018.051

Intestinal dysbiosis and hormonal neuroendocrine secretion in the fibromyalgic patient

Giovanni Tomaselloa, Margherita Mazzolaa,b, Vincenzo Boscoc, Giulia Tomasellod, Provvidenza Damianib,e, Emanuele Sinagrab,f, Francesco Carinia,b,e
a Department of Experimental Biomedicine and Clinical Neuroscience, Section of Human Anatomy, (BIONEC), School of Medicine and Surgery, University of Palermo, Palermo, Italy
b Euro-Mediterranean Institute of Science and Technology (IEMEST), Palermo, Italy
c School of Medicine, Palermo, Italy
d Kore University, Enna, Italy
e Universitary Hospital, AOUP "P. Giaccone", Palermo, Italy
f Giglio Hospital, Cefalu, Italy

Fibromyalgia is a rheumatic syndrome and its pathogenesis is controversial. The recent literature has placed considerable attention on the link between alteration of the intestinal microbiota and fibromyalgia, emphasizing the close connection between the neuroenteric system and the CNS. This study aims to evaluate the probable relationship between intestinal dysbiosis and altered secretion of hormones and vitamins such as cortisol, serotonin, Vitamin D and thyroid hormones in a patient with fibromyalgia.

Keywords: microbiota, fibromyalgia, hormones, dysbiosis, serotonin, cortisol, vitamin D

Received: April 6, 2018; Accepted: August 30, 2018; Prepublished online: September 11, 2018; Published: November 14, 2018  Show citation

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Tomasello, G., Mazzola, M., Bosco, V., Tomasello, G., Damiani, P., Sinagra, E., & Carini, F. (2018). Intestinal dysbiosis and hormonal neuroendocrine secretion in the fibromyalgic patient. Biomedical papers, 162(4), 258-262. doi: 10.5507/bp.2018.051
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