Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2024, 168(2):156-161 | DOI: 10.5507/bp.2023.027

Utility of fine-needle aspiration biopsy (FNAB) in parotid pleomorphic adenoma diagnosis and management

Alzbeta Fikova1, Stepan Novak1, David Kalfert1, Martin Kuchar2, Michal Zabrodsky1, Lucie Dostalova1, Jan Balko3, Jan Plzak1
1 Department of Otorhinolaryngology and Head and Neck Surgery, First Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic
2 Department of Otorhinolaryngology and Head and Neck Surgery, Bulovka University Hospital, Prague, Czech Republic
3 Department of Pathology and Molecular Medicine, Second Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic

Purpose. Pleomorphic adenoma (PA), the most common benign tumour of the parotid gland, requires accurate preoperative diagnosis owing to its capacity for malignant transformation. The aim of this study was to evaluate our experience with ultrasound-guided fine-needle aspiration biopsy (FNAB) in the diagnostic algorithm for patients with PA and to assess clinical outcomes for those with different surgical approaches.

Material and Methods: We carried out a retrospective analysis of patients treated for parotid gland mass between 2010 and 2016. These had had preoperative FNAB and had undergone subsequent surgery.

Results: 165 patients had FNAB with the result of PA and the definitive histology confirmed PA in 159 cases (96.4%). On the other hand, in 179 patients, the definitive histology showed PA and the preoperative FNAB result corresponded in 159 cases (88.9%). The measured sensitivity, specificity and accuracy of ultrasound-guided FNAB in the diagnosis of PA were, respectively, 88.83%, 96.23% and 92.31%. Most of the patients underwent superficial or partial superficial parotidectomy, followed by extracapsular dissection which was associated with statistically lower risk of facial nerve injury (P=0.04).

Conclusion: Ultrasound-guided FNAB is simple, accurate and valuable in the diagnosis of PA and provides results that can lead to the choice of less invasive operative treatment.

Keywords: pleomorphic adenoma, fine-needle aspiration biopsy, ultrasound, parotid gland tumours

Received: March 23, 2023; Revised: April 28, 2023; Accepted: June 13, 2023; Prepublished online: July 10, 2023; Published: June 10, 2024  Show citation

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Fikova, A., Novak, S., Kalfert, D., Kuchar, M., Zabrodsky, M., Dostalova, L., Balko, J., & Plzak, J. (2024). Utility of fine-needle aspiration biopsy (FNAB) in parotid pleomorphic adenoma diagnosis and management. Biomedical papers, 168(2), 156-161. doi: 10.5507/bp.2023.027
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