Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2022, 166(2):168-172 | DOI: 10.5507/bp.2021.013

Cardiac device-related infective endocarditis in the Czech Republic: Prospective data from the ESC EORP EURO-ENDO registry

Jan Latala, Michal Pazdernikb, c, Maria Holickad, Radek Pelouche, Jiri Widimskyf, Jiri Pudichg, Radek Vancatah, Michal Siraneci, Kamila Blechovaj, k, Tadeas Buttac, Marketa Mikulcovam, Michal Mikulicam, Peter Wohlfahrtn, Martin Hutyraa, Jan Preceka
a Department of Internal Medicine I - Cardiology, University Hospital Olomouc, Czech Republic
b Department of Cardiology, IKEM, Prague, Czech Republic
c Department of Cardiology, 2nd Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic
d Department of Internal Medicine and Cardiology, University Hospital Brno, Czech Republic
e 1st Department of Internal Medicine - Cardioangiology, Faculty Hospital in Hradec Kralove, Czech Republic
f Department of Cardiology, Regional Hospital Liberec, Czech Republic
g Department of Cardiovascular Diseases, University Hospital in Ostrava, Czech Republic
h Department of Cardiology, University Hospital Pilsen and Faculty of Medicine in Pilsen, Charles University, Pilsen, Czech Republic
i 2nd Department of Internal Cardiovascular Medicine, First Faculty of Medicine, Charles University and General University Hospital in Prague, Czech Republic
j Cardiocenter, 3rd Faculty of Medicine, Charles University, Prague, Czech Republic
k Department of Cardiac Surgery, Na Homolce Hospital, Prague, Czech Republic
m Cardiovascular Center for Adults, Tomas Bata Regional Hospital, Zlin, Czech Republic
n Center for Cardiovascular Prevention, 1st Faculty of Medicine, Charles University and Thomayer Hospital, Prague, Czech Republic

Aim: Understanding cardiac electronic device infective endocarditis epidemiology is essential for the management of this serious complication. Only monocentric and limited data have been published regarding patients in the Czech republic so far. The aim of this study was to describe the current profile, microbiology and clinical characteristics of this population.

Patients and Methods: National data from the prospective ESC-EORP EURO-ENDO registry were collected. 57 consecutive patients with a diagnosis of cardiac device-related infective endocarditis (CDRIE) from 11 Czech centres were included.

Results: Staphylococcus spp. was responsible for 43.9% of isolates, whereas Culture negative endocarditis was documented in 26.3% episodes. The most frequent complications under therapy were acute renal failure (17.5%), septic shock and heart failure (both 10.5%). Extraction of device was performed in 75.4% of all patients, and the 1-year mortality was 22.5%.

Conclusions: The high proportion of culture-negative endocarditis is alarming and warrants further investigation. Cardiac device related infective endocarditis is a serious complication with a high 1-year mortality in a highly polymorbid spectrum of patients.

Keywords: cardiac electronic device infective endocarditis, infective endocarditis, cardiac device complication

Received: November 19, 2020; Revised: January 29, 2021; Accepted: February 1, 2021; Prepublished online: February 22, 2021; Published: May 13, 2022  Show citation

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Latal, J., Pazdernik, M., Holicka, M., Pelouch, R., Widimsky, J., Pudich, J., ... Precek, J. (2022). Cardiac device-related infective endocarditis in the Czech Republic: Prospective data from the ESC EORP EURO-ENDO registry. Biomedical papers, 166(2), 168-172. doi: 10.5507/bp.2021.013
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