Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2022, 166(1):51-56 | DOI: 10.5507/bp.2021.001

Aortic propagation velocity in the prediction of coronary artery disease severity

Eftal Murat Bakircia, Husnu Degirmencia, Hakan Dumanb, Selami Demirellic, Hikmet Hamura, Mutlu Buyuklua, Gokhan Ceyhund, Ergun Kutlusoya
a Department of Cardiology, Faculty of Medicine, Erzincan Binali Yildirim University, Erzincan, Turkey
b Department of Cardiology, Faculty of Medicine, Recep Tayyip Erdogan University, Rize, Turkey
c Department of Cardiology, Kayseri Education and Research Hospital, Kayseri, Turkey
d Department of Cardiology, Faculty of Medicine, Ataturk University, Erzurum, Turkey

Aims: To investigate the association of the aortic propagation velocity (APV) with coronary artery disease (CAD) in patients with stable angina pectoris (SAP) through SYNTAX scores (SS).

Methods: The study population comprised 214 SAP subjects who received a coronary angiography. The APV and carotid intima-media thickness (CIMT) were examined and SS was calculated. Subjects were grouped following specific SS criteria: SS less than 22 (low) and SS greater than or equal to 22 (high).

Results: High SS subjects had lower APV compared to low SS [39.0 (32.0-51.7) vs. 55.0 (45.0-62.0) cm/s, respectively; P<0.001] and higher CIMT (0.86 ± 0.24 vs. 0.74 ± 0.21 mm, respectively; P<0.001). APV demonstrated a negative correlation with the CIMT (r=-0.239, P<0.001), age (r=-0.188, P=0.006) , and SS (r=-0.561, P<0.001) and showed a positive association with LV ejection fraction (r=0.163, P=0.017). APV, CIMT, diabetes, low-density lipoprotein cholesterol (LDL-C), and age were determined to be markers independently of a high SS.

Conclusion: APV, CIMT, diabetes, LDL-C and age are independently linked to the CAD severity of SAP subjects. Decreased APV, an indicator of subclinical atherosclerosis, may independently help determine the severity of atherosclerotic CAD in SAP patients.

Keywords: APV, CIMT, CAD, SYNTAX score

Received: October 3, 2020; Revised: December 5, 2020; Accepted: January 7, 2021; Prepublished online: February 22, 2021; Published: March 1, 2022  Show citation

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Bakirci, E.M., Degirmenci, H., Duman, H., Demirelli, S., Hamur, H., Buyuklu, M., Ceyhun, G., & Kutlusoy, E. (2022). Aortic propagation velocity in the prediction of coronary artery disease severity. Biomedical papers, 166(1), 51-56. doi: 10.5507/bp.2021.001
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