Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2022, 166(1):21-27 | DOI: 10.5507/bp.2021.059

Lesions in the oral cavity and esophagus caused by prescribed drugs: A review

Snezana Tesic-Rajkovic^{a, b}, Biljana Radovanovic-Dinic^{a, b}

^a Faculty of Medicine, University of Nis, Serbia

^b Clinic for Gastroenterology and Hepatology, University Clinical Center, Nis, Serbia

Almost all drugs, including some plant-based compounds, can have adverse effects, about 10% of which are expressed at the level of the digestive tract and in some cases resemble gastrointestinal diseases. Most commonly manifest as difficult and/or painful swallowing, nausea, vomiting, diarrhea and constipation. In rare cases, lesions caused by medications may be complicated by bleeding, strictures and perforations and can manifest in all segments of the gastrointestinal tract (GIT). The diagnosis is made from a detailed medical history and clinical examination inter alia. and best confirmed by proximal or distal endoscopy.

Keywords: esophagus, drugs, oral cavity, side-effects

Received: July 24, 2021; Revised: September 19, 2021; Accepted: October 18, 2021; Prepublished online: November 5, 2021; Published: March 1, 2022  Show citation