Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2021, 165(3):342-345 | DOI: 10.5507/bp.2020.032

Low-grade fibromyxoid sarcoma of the maxillary sinus

Vladimir Koucky^a, David Kalfert^a, Daniela Kodetova Novakova^b, Jan Plzak

^a Department of Otorhinolaryngology and Head and Neck Surgery, First Faculty of Medicine, Charles University and Motol University Hospital, V Uvalu 84, 15006, Prague, Czech Republic

^b Department of Pathology and Molecular Medicine, Second Faculty of Medicine, Charles University and Motol University Hospital, V Uvalu 84, 15006, Prague, Czech Republic

Background: Low-grade fibromyxoid sarcoma (LGFMS) is a rare malignant tumor. Moreover, only 3 cases of LGFMS originating from the nasal cavity and/or paranasal sinuses have been published so far.

Methods: Two patients with histologically confirmed LGFMS of the maxillary sinus were primarily treated by open and endoscopic surgery. In one case adjuvant radiotherapy was indicated because of the uncertainty of the surgical margins.

Results: Both surgeries were technically demanding and accompanied by significant bleeding from the tumors. Despite the extensive interventions there were no postoperative complications and no significant morbidity of the patients. There is no evidence of the disease 148 and 65 months after the treatment.

Conclusions: Regardless of the excellent post-treatment results, based on our experience, preoperative embolisation of the tumor should be considered prior to the surgical resection.

Keywords: sarcoma, low-grade fibromyxoid sarcoma, head and neck, maxillary sinus, endoscopic sinus surgery

Received: January 27, 2020; Revised: July 6, 2020; Accepted: July 15, 2020; Prepublished online: July 20, 2020; Published: September 20, 2021  Show citation