Biomedical Papers, 2013 (vol. 157), issue 2

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2013, 157(2):98-104 | 10.5507/bp.2013.042

Renal manifestations of rheumatic diseases. A review

Pavel Horaka, Andrea Smrzovaa, Karel Krejcia, Tomas Tichyb, Josef Zadrazila, Martina Skacelovaa
a Department of Internal Medicine III - Nephrology, Rheumatology and Endocrinology, Faculty of Medicine and Dentistry, Palacky University Olomouc, Czech Republic
b Department of Clinical and Molecular Pathology, Faculty of Medicine and Dentistry, Palacky University Olomouc

Background: Renal manifestations of rheumatic diaseases are sometimes very discrete and mild. At others, they can present the leading symptomatology of a given disease. Systemic lupus erythematosus, systemic scleroderma, renal vasculitis, rheumatoid arthritis, mixed connective tissue disease, Sjögren's syndrome and gout can all manifest in or be accompanied by renal impairment.

Methods and Results: The authors reviewed the literature on renal manifestation of rheumatic diseases using the key words, lupus erythematosus, systemic autoimmune diseases, rheumatoid arthritis, vasculitis and gout. The review below is accompanied by their own histological findings.

Conclusion: Diagnosis requires proper interpretation of the clinical situation, laboratory results and image analysis methods plus close interdisciplinary collaboration between nephrologist and clinical pathologist/nephropathologist.

Keywords: kidney, rheumatic diseases, systemic autoimmune diseases, rheumatoid arthritis, vasculitis, gout, drugs

Received: January 24, 2013; Accepted: May 23, 2013; Published: June 7, 2013


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