Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2006, 150(2):271-273 | DOI: 10.5507/bp.2006.040

SELECTED PREGNANCY VARIABLES IN WOMEN WITH PLACENTAL ABRUPTION

Martin Prochazka^a, Marek Lubusky^a, Ludek Slavik^b, Petr Hrachovec^a, Petr Zielina^a, Milan Kudela^a, Pelle G. Lindqvist^c

^a Department of Obstetrics and Gynecology, Faculty of Medicine and Dentistry, Palacky University, Olomouc, Czech Republic

^b Department of Hematooncology, Faculty of Medicine and Dentistry, Palacky University, Olomouc

^c Department of Obstetrics and Gynaecology, University Hospital MAS, Malmö, Sweden

Objective: The aim of this study was to investigate risk factors for placental abruption and to determine if anamnestic variables such as inherited thrombosis or recurrent fetal loss might be used as a predictor for placental abruption.

Methods: A retrospective case-control study at the University Hospital, Palacky University, Olomouc, Czech Republic. One hundred and eighty women with placental abruptio out of 20,175 deliveries (0.79 %) who were compared to 196 unselected pregnant women. A detailed anamnesis was taken.

Results: Compared to controls, women with placental abruptio had a 12-fold increased prevalence of prior recurrent fetal loss and a 6-fold increased prevalence of inherited thrombosis.

Conclusions: We found that recurrent fetal loss, and inherited thrombosis may be significant risk factors for placental abruptio.

Keywords: Hereredity factors in thrombosis, Placental abruption, Fetal loss, Risk factors

Received: August 13, 2006; Accepted: October 30, 2006; Published: December 1, 2006  Show citation