Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2005, 149(2):217-219 | DOI: 10.5507/bp.2005.029
EXPERIMENTAL TOXICOLOGY IN SILICO
- National Institute of Public Health, ©robárova 48, 10042 Praha 10
A review on applicability of in silico methods for toxicity testing by calculation for regulatory purposes, their survey and background of QSAR (Quantitative Structure-Activity Relationships) analysis are presented.
Keywords: Toxicity Testing, In Silico Methods, QSAR, Validation of Computer Models
Received: June 10, 2005; Accepted: September 25, 2005; Published: December 1, 2005 Show citation
References
- Tichý M. Biological activities of xenobiotics and their chemical structure (in Czech). Praha: Avicenum, 1983.
- Tichý M, Halousková O. (eds.) Alternative methods of toxicity testing of chemicals (in Czech). Proceedings of a workshop on the same title, Chrudim-Píą»ovy, Czech Republic, April 27-28, 2005. Vodní zdroje EKOMONITOR, 2005.
- Cronin MTD, Walker JD, Jaworska JS, Comber MHI, Watts CD, Worth AP. (2003) Use of QSARs in international decision-making frameworks to predict ecologic effects and environmental fate of chemical substances. Environ Health Persp 111, 1376-90.
Go to original source...
Go to PubMed...
- Cronin MTD, Jaworska JS, Walker JD, Comber MHI, Watts CD, Worth AP. (2003) Use of QSARs in international decision-making frameworks to predict health effects of chemical substances. Environ Health Persp 111, 1391-401.
Go to original source...
Go to PubMed...
- Erriksson L, Jaworska J, Worth AP, Cronin MTD, McDowell RM, Gramatica P. (2003) Methods of reliability and uncertainty assessment and for applicability evaluations of classification - a regression- based QSARs. Environ Health Persp 111, 1361-75.
Go to original source...
Go to PubMed...
- Jaworska J, Comber M, Auer C, Van Leeuwen CJ. (2003) Summary of a workshop on regulatory acceptance of (Q)SAR for human health and environmental endpoints. Environ Health Persp 111, 1358-60.
Go to original source...
Go to PubMed...