Biomed. Papers 147(2), 177-180 (2003) | DOI: 10.5507/bp.2003.025

USE OF CYSTATIN C DETERMINATION IN CLINICAL DIAGNOSTICS

Jan Mareša, David Stejskalb, Jitka Vavrouškovác, Karel Urbáneka, Roman Herziga, Petr Hluštíka
a Clinic of Neurology, Teaching Hospital, Olomouc
b Department of Laboratory Medicine, Hospital Šternberk
c Department of Neurology, Hospital Šternberk

This paper presents a current view of the possible clinical uses of cystatin C determination. Cystatin C is an inhibitor of cysteine proteases, and relatively stable in the systemic circulation it is comparatively easily determined. Although in clinical practice it is known primarily as a relatively reliable and endogenous marker for glomerular filtration, lately cystatin C analysis has been discussed in connection with the diagnostics of a variety of diseases such as early atherosclerosis, Alzheimer's dementia, vascular aneurysms, hyperhomocysteinaemia and other neurodegenerative diseases.

Keywords: Keywords: Cystatin C, Biochemical diagnostics, Alzheimer’s dementia, Early atherosclerosis, Vascular aneurysms, Hyperhomocysteinaemia, Neurodegenerative diseases

Received: October 21, 2003; Accepted: December 10, 2003; Published: December 1, 2003  Show citation

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Mareš, J., Stejskal, D., Vavroušková, J., Urbánek, K., Herzig, R., & Hluštík, P. (2003). USE OF CYSTATIN C DETERMINATION IN CLINICAL DIAGNOSTICS. Biomedical papers, 147(2), 177-180. doi: 10.5507/bp.2003.025
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