Biomed. Papers 147(1), 37-41 (2003) | DOI: 10.5507/bp.2003.005

PATHOBIOLOGY OF ANDROGENETIC ALOPECIA

Michala Fiuráškováa, Renata Kučerováb, Zdeněk Kolářa
a Institute of Pathology, Laboratory of Molecular Pathology, Faculty of Medicine, Palacky University, Hněvotínská 3, Olomouc 775 15, Czech Republic
b Clinic of Dermatovenereology, Faculty of Medicine and Faculty Hospital, I. P. Pavlova 6, 775 20, Czech Republic

Human hair morphogenesis is a dynamic process caused by the remodelling of the skin. Hair growth is cyclic in mammals consisting of three distinct stages: an active stage (anagen), a regressive stage (catagen), and a resting stage (telogen). One disorder in this process is gradual balding of the scalp called androgenetic alopecia. Little is known about the cell biological or molecular mechanisms involved and thus very little treatment is currently available. In this review we focus on the most significant parameters affecting hair growth which participate in baldness.

Keywords: Androgenetic alopecia, Hair-growth cycle, Androgens 5α-Reductase, β-Catenin, p63

Received: May 20, 2003; Published: November 1, 2003  Show citation

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Fiurášková, M., Kučerová, R., & Kolář, Z. (2003). PATHOBIOLOGY OF ANDROGENETIC ALOPECIA. Biomedical papers, 147(1), 37-41. doi: 10.5507/bp.2003.005
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