RT Journal Article SR Electronic A1 Troubil, Martin A1 Lonsky, Vladimir A1 Gwozdziewicz, Marek A1 Bruk, Vilem T1 PERSISTENT AND RECURRENT ISCHEMIC MITRAL REGURGITATION JF Biomedical papers YR 2010 VO 154 IS 2 SP 141 OP 145 DO 10.5507/bp.2010.021 UL https://biomed.papers.upol.cz/artkey/bio-201002-0005.php AB Backround. Ischemic mitral regurgitation (IMR) is a consequence of coronary artery disease and the main underlying mechanism is augmented leaflet tethering due to outward displacement of the papillary muscles. Although mitral annuloplasty combined with coronary revascularization is usually effective in the treatment of IMR, occasionally the regurgitation can persist or recur and this can affect patient prognosis. Methods: We searched Medline and Google scholar database for articles published since 1996 to June 2009. Search terms included ischemic mitral regurgitation, recurrent mitral regurgitation, persistent mitral regurgitation and annuloplasty failure. Conclusion: This article reviews current knowledge about IMR, the reasons and mechanisms of persistent and recurrent mitral regurgitation. We review clinic and echocardiographic predictive factors associated with persistence a recurrence of mitral regurgitation after annuloplasty.