RT Journal Article
SR Electronic
A1 Vagnerová, Radomíra
A1 Kučera, Tomáš
T1 REBUILDING OF RAT INTESTINAL MUCOUS EPITHELIUM IN PRENATAL ONTOGENESIS
JF Biomedical papers
YR 2004
VO 148
IS 2
SP 253
OP 254
DO 10.5507/bp.2004.053
UL https://biomed.papers.upol.cz/artkey/bio-200402-0034.php
AB Morphological differentiation of the intestinal epithelium in the laboratory rat occurs between the 16<sup>th</sup> and 21<sup>st</sup> day of prenatal development. The pseudostratified epithelium is rebuilt into simple epithelium of the future lining. A characteristic sign of this rebuilding is formation of primitive folds, villi and intraepithelial vacuoles coresponding in submicroscopic picture with a secondary luminization. On the tips of folds and villi groups of cells released from the epithelium are observed. In these cells expression of activated caspase-3 confirms the presence of apoptosis in the process of cell death during epithelium rebuilding.