PT  - JOURNAL ARTICLE
AU  - Vagnerová, Radomíra
AU  - Kučera, Tomáš
TI  - REBUILDING OF RAT INTESTINAL MUCOUS EPITHELIUM IN PRENATAL ONTOGENESIS
DP  - 2004 Dec 1
TA  - Biomedical papers
PG  - 253--254
VI  - 148
IP  - 2
AID - 10.5507/bp.2004.053
IS  - 12138118
AB  - Morphological differentiation of the intestinal epithelium in the laboratory rat occurs between the 16<sup>th</sup> and 21<sup>st</sup> day of prenatal development. The pseudostratified epithelium is rebuilt into simple epithelium of the future lining. A characteristic sign of this rebuilding is formation of primitive folds, villi and intraepithelial vacuoles coresponding in submicroscopic picture with a secondary luminization. On the tips of folds and villi groups of cells released from the epithelium are observed. In these cells expression of activated caspase-3 confirms the presence of apoptosis in the process of cell death during epithelium rebuilding.