PT Journal
AU Vagnerova, R
   Kucera, T
TI REBUILDING OF RAT INTESTINAL MUCOUS EPITHELIUM IN PRENATAL ONTOGENESIS
SO Biomedical papers
PY 2004
BP 253
EP 254
VL 148
IS 2
DI 10.5507/bp.2004.053
DE Rat intestinal epithelium/Prenatal differentiation/Apoptosis
AB Morphological differentiation of the intestinal epithelium in the laboratory rat occurs between the 16<sup>th</sup> and 21<sup>st</sup> day of prenatal development. The pseudostratified epithelium is rebuilt into simple epithelium of the future lining. A characteristic sign of this rebuilding is formation of primitive folds, villi and intraepithelial vacuoles coresponding in submicroscopic picture with a secondary luminization. On the tips of folds and villi groups of cells released from the epithelium are observed. In these cells expression of activated caspase-3 confirms the presence of apoptosis in the process of cell death during epithelium rebuilding.
ER