RT Journal Article
SR Electronic
A1 Mareš, Jan
A1 Stejskal, David
A1 Vavroušková, Jitka
A1 Urbánek, Karel
A1 Herzig, Roman
A1 Hluštík, Petr
T1 USE OF CYSTATIN C DETERMINATION IN CLINICAL DIAGNOSTICS
JF Biomedical papers
YR 2003
VO 147
IS 2
SP 177
OP 180
DO 10.5507/bp.2003.025
UL https://biomed.papers.upol.cz/artkey/bio-200302-0009.php
AB This paper presents a current view of the possible clinical uses of cystatin C determination. Cystatin C is an inhibitor of cysteine proteases, and relatively stable in the systemic circulation it is comparatively easily determined. Although in clinical practice it is known primarily as a relatively reliable and endogenous marker for glomerular filtration, lately cystatin C analysis has been discussed in connection with the diagnostics of a variety of diseases such as early atherosclerosis, Alzheimer's dementia, vascular aneurysms, hyperhomocysteinaemia and other neurodegenerative diseases.