PT  - JOURNAL ARTICLE
AU  - Mareš, Jan
AU  - Stejskal, David
AU  - Vavroušková, Jitka
AU  - Urbánek, Karel
AU  - Herzig, Roman
AU  - Hluštík, Petr
TI  - USE OF CYSTATIN C DETERMINATION IN CLINICAL DIAGNOSTICS
DP  - 2003 Dec 1
TA  - Biomedical papers
PG  - 177--180
VI  - 147
IP  - 2
AID - 10.5507/bp.2003.025
IS  - 12138118
AB  - This paper presents a current view of the possible clinical uses of cystatin C determination. Cystatin C is an inhibitor of cysteine proteases, and relatively stable in the systemic circulation it is comparatively easily determined. Although in clinical practice it is known primarily as a relatively reliable and endogenous marker for glomerular filtration, lately cystatin C analysis has been discussed in connection with the diagnostics of a variety of diseases such as early atherosclerosis, Alzheimer's dementia, vascular aneurysms, hyperhomocysteinaemia and other neurodegenerative diseases.