PT Journal AU Fiuraskova, M Kucerova, R Kolar, Z TI PATHOBIOLOGY OF ANDROGENETIC ALOPECIA SO Biomedical papers PY 2003 BP 37 EP 41 VL 147 IS 1 DI 10.5507/bp.2003.005 DE Androgenetic alopecia / Hair-growth cycle / Androgens 5α-Reductase / β-Catenin / p63 AB Human hair morphogenesis is a dynamic process caused by the remodelling of the skin. Hair growth is cyclic in mammals consisting of three distinct stages: an active stage (anagen), a regressive stage (catagen), and a resting stage (telogen). One disorder in this process is gradual balding of the scalp called androgenetic alopecia. Little is known about the cell biological or molecular mechanisms involved and thus very little treatment is currently available. In this review we focus on the most significant parameters affecting hair growth which participate in baldness. ER