RT Journal Article SR Electronic A1 Stejskal, David A1 Bartek, Josef A1 Pastorková, Radmila A1 Růžička, Viktor A1 Oral, Ivo A1 Horalík, Dalimil T1 OSTEOPROTEGERIN, RANK, RANKL JF Biomedical papers YR 2001 VO 145 IS 2 SP 61 OP 64 DO 10.5507/bp.2001.013 UL https://biomed.papers.upol.cz/artkey/bio-200102-0008.php AB Osteoprotegerin, RANK (Receptor Activator of Nuclear factor kappa B) and RANKL (Receptor Activator ofNuclear faktor kappa B ligand) became the aim of intensive researche. RANK is considered as a hematopoieticsurface receptor controling osteoclastogenesis and calcium metabolism. RANKL may promote osteoresorption byinduction of cathepsin K gene expression. The present paper summarizes the most significant data in osteoprotegerin,RANK and RANKL problems obtained.