PT - JOURNAL ARTICLE AU - Stejskal, David AU - Bartek, Josef AU - Pastorková, Radmila AU - Růžička, Viktor AU - Oral, Ivo AU - Horalík, Dalimil TI - OSTEOPROTEGERIN, RANK, RANKL DP - 2001 Dec 1 TA - Biomedical papers PG - 61--64 VI - 145 IP - 2 AID - 10.5507/bp.2001.013 IS - 12138118 AB - Osteoprotegerin, RANK (Receptor Activator of Nuclear factor kappa B) and RANKL (Receptor Activator ofNuclear faktor kappa B ligand) became the aim of intensive researche. RANK is considered as a hematopoieticsurface receptor controling osteoclastogenesis and calcium metabolism. RANKL may promote osteoresorption byinduction of cathepsin K gene expression. The present paper summarizes the most significant data in osteoprotegerin,RANK and RANKL problems obtained.