PT Journal AU Stejskal, D Bartek, J Pastorkova, R Ruzicka, V Oral, I Horalik, D TI OSTEOPROTEGERIN, RANK, RANKL SO Biomedical papers PY 2001 BP 61 EP 64 VL 145 IS 2 DI 10.5507/bp.2001.013 DE Osteoprotegerin / RANK / RANKL AB Osteoprotegerin, RANK (Receptor Activator of Nuclear factor kappa B) and RANKL (Receptor Activator ofNuclear faktor kappa B ligand) became the aim of intensive researche. RANK is considered as a hematopoieticsurface receptor controling osteoclastogenesis and calcium metabolism. RANKL may promote osteoresorption byinduction of cathepsin K gene expression. The present paper summarizes the most significant data in osteoprotegerin,RANK and RANKL problems obtained. ER