RT Journal Article
SR Electronic
A1 Gibejová, Agáta
T1 CHEMOKINE RECEPTORS
JF Biomedical papers
YR 2000
VO 144
IS 1
SP 9
OP 18
DO 10.5507/bp.2000.001
UL https://biomed.papers.upol.cz/artkey/bio-200001-0001.php
AB Chemokines mediate their multiple effects by binding to a variety of specific receptors, that comprise a subfamilyof rhodopsin-like, 7-transmembrane domain receptors, coupled to G proteins. Some of these receptors serve ascoreceptors for HIV, some of them could be expressed as markers for T lymphocyte functional differentiation. Thisreview aims at summarising data on chemokine receptors, their function in vivo, their target cells and it alsomentions association of chemokine receptor polymorphisms with human disease.