PT  - JOURNAL ARTICLE
AU  - Gibejová, Agáta
TI  - CHEMOKINE RECEPTORS
DP  - 2000 Jul 1
TA  - Biomedical papers
PG  - 9--18
VI  - 144
IP  - 1
AID - 10.5507/bp.2000.001
IS  - 12138118
AB  - Chemokines mediate their multiple effects by binding to a variety of specific receptors, that comprise a subfamilyof rhodopsin-like, 7-transmembrane domain receptors, coupled to G proteins. Some of these receptors serve ascoreceptors for HIV, some of them could be expressed as markers for T lymphocyte functional differentiation. Thisreview aims at summarising data on chemokine receptors, their function in vivo, their target cells and it alsomentions association of chemokine receptor polymorphisms with human disease.