PT Journal
AU Starek, I
   Salzman, R
   Skalova, A
TI Heterotopic acinic cell carcinoma and its clinical implications
SO Biomedical papers
PY 2021
BP 13
EP 18
VL 165
IS 1
DI 10.5507/bp.2020.047
DE acinic cell carcinoma; heterotopia; lymph node; salivary gland
AB This is a review of the clinical and histopathological published data on very rare heterotopic acinic cell carcinomas (AcCCs) with suggested optimal management. Extrasalivary AcCCs originate primarily in parotid lymph nodes. They present at low clinical stage, show mostly low-grade histopathology and are circumscribed with a complete nodal capsule. Extracapsular dissection was advocated as adequate therapy. In rare cases with positive surgical margins, a completion parotidectomy or adjuvant radiotherapy should follow. Heterotopic high-grade AcCCs are rare, necessitating radical surgery including neck dissection and adjuvant radiotherapy. The short term prognosis is excellent, long term outcomes are not known. Longer term follow-up is essential.
ER