RT Journal Article
SR Electronic
A1 Skala, Tomas
A1 Tudos, Zbynek
A1 Moravec, Ondrej
A1 Hutyra, Martin
A1 Precek, Jan
A1 Skalova, Jitka
A1 Klementova, Olga
A1 Zapletalova, Jana
A1 Taborsky, Milos
T1 Atrial fibrillation inducibility after pulmonary vein isolation under general anaesthesia
JF Biomedical papers
YR 2020
VO 164
IS 3
SP 261
OP 266
DO 10.5507/bp.2019.004
UL https://biomed.papers.upol.cz/artkey/bio-202003-0006.php
AB Aims: Atrial fibrillation (AF) inducibility with rapid atrial pacing following AF ablation is associated with higher risk of AF recurrence. The predictive value of AF inducibility in paroxysmal AF patients after pulmonary vein isolation (PVI), done under general anaesthesia (GA), remains questionable since GA might alter AF inducibility and/or sustainability. Methods: Consecutive patients (n = 120) with paroxysmal AF without prior catheter ablation (CA) were enlisted in the study. All patients were ablated under GA. We have used a point-by-point CA and elimination of dormant conduction after adenosine in all patients. A predefined stimulation protocol was used to induce arrhythmias after PVI. Regular supraventricular tachycardias were mapped and ablated. Patients were divided into 3 subgroups - noninducible, inducible AF with spontaneous termination in five minutes, inducible AF without spontaneous termination. During 12 months of follow-up, all patients were examined four-times with 7-day ECG recordings. Results: There was no statistical difference between the three subgroups in a rate of arrhythmia recurrence (11.1 vs. 27.5 vs. 27.3%, P=0.387), despite a clear trend to a better success rate in the non-inducible group. The subgroups did not differ in left atrial (LA) diameter (41.0±6, 43.0±7, 42.0±5 mm, P=0.962) or in any other baseline parameter. Conclusion: AF inducibility as well as presence or absence of its early spontaneous termination after PVI done under general anaesthesia in paroxysmal AF patients were not useful as predictors of procedural failure.