PT - JOURNAL ARTICLE AU - Gorican, Karel AU - Chochola, Miroslav AU - Kocik, Miroslav AU - Zak, Ales TI - Diagnostic criteria for the determination of clinically significant internal carotid artery stenosis using duplex ultrasound DP - 2020 Sep 17 TA - Biomedical papers PG - 255--260 VI - 164 IP - 3 AID - 10.5507/bp.2019.029 IS - 12138118 AB - Background: Carotid endarterectomy is beneficial in symptomatic patients with ≥70% stenosis at the bifurcation of the internal carotid artery. The fact that the duplex ultrasound is widely used, inexpensive and non-invasive for examination of the carotid arteries underlines the importance of high accuracy of this method for grading internal artery stenosis. Patients and Methods: Duplex scans and arteriograms of carotid arteries of 142 patients were reviewed. Peak and end-diastolic velocities of the common and internal carotid arteries were recorded, and the percent stenosis of the internal carotid artery was determined by arteriogram. Receiver-operator characteristic curves of sensitivity, specificity, positive and negative predictive values and accuracy were determined. Results: The recommended criteria for the detection of ≥70% stenosis of the internal carotid artery were: peak systolic velocity in the internal carotid artery ≥215 cm/s, end-diastolic velocity in the internal carotid artery ≥65 cm/s, ratio of peak systolic velocities in the internal and common carotid arteries ≥2.7 and ratio of the end-diastolic velocities of the internal and common carotid arteries ≥3.7. Conclusion: These criteria allow for reliable determination of internal carotid artery stenosis ≥70% by duplex ultrasound.