PT  - JOURNAL ARTICLE
AU  - Zarobkiewicz, Michal Konrad
AU  - Kowalska, Wioleta
AU  - Slawinski, Miroslaw
AU  - Rolinski, Jacek
AU  - Bojarska-Junak, Agnieszka
TI  - The role of interleukin 22 in multiple sclerosis and its association with c-Maf and AHR
DP  - 2019 Sep 23
TA  - Biomedical papers
PG  - 200--206
VI  - 163
IP  - 3
IS  - 12138118
AB  - The aim of this paper was to summarise knowledge of IL-22 involvement in multiple sclerosis (MS) and the possible link between IL-22 and two transcription factors - AHR and c-Maf. The conclusion is that despite numerous studies, the exact role of IL-22 in the pathogenesis of MS is still unknown. The expression and function of c-Maf in MS have not been studied. It seems that the functions of c-Maf and AHR are at least partly connected with IL-22, as both directly or indirectly influence the regulation of IL-22 expression. This possible connection has never been studied in MS.