PT Journal AU Spacek, M Zemanek, D Hutyra, M Sluka, M Taborsky, M TI Vulnerable atherosclerotic plaque - a review of current concepts and advanced imaging SO Biomedical papers PY 2018 BP 10 EP 17 VL 162 IS 1 DI 10.5507/bp.2018.004 DE atherosclerosis; vulnerable plaque; carotid artery; coronary artery; imaging AB Atherosclerosis is the most common cause of both carotid and coronary steno-occlusive disease. Rupture of an atherosclerotic plaque may lead to the formation of an overlying thrombosis resulting in complete arterial occlusion or downstream embolism. Clinically, this may manifest as a stroke or acute myocardial infarction, the overall leading causes of mortality and disability in developed countries. In this article, we summarize current concepts of the development of vulnerable plaque and provide an overview of commonly used imaging methods that may suggest/indicate atherosclerotic plaque vulnerability. ER