RT Journal Article
SR Electronic
A1 Tomasello, Giovanni
A1 Mazzola, Margherita
A1 Leone, Angelo
A1 Sinagra, Emanuele
A1 Zummo, Giovanni
A1 Farina, Felicia
A1 Damiani, Provvidenza
A1 Cappello, Francesco
A1 Gerges Geagea, Alice
A1 Jurjus, Abdo
A1 Bou Assi, Tarek
A1 Messina, Massimiliano
A1 Carini, Francesco
T1 Nutrition, oxidative stress and intestinal dysbiosis: Influence of diet on gut microbiota in inflammatory bowel diseases
JF Biomedical papers
YR 2016
VO 160
IS 4
SP 461
OP 466
DO 10.5507/bp.2016.052
UL https://biomed.papers.upol.cz/artkey/bio-201604-0001.php
AB Background: Microbiota refers to the population of microorganisms (bacteria, viruses and fungi) that inhabit the entire gastrointestinal tract, more particularly the colon whose role is to maintain the integrity of the intestinal mucosa and control the proliferation of pathogenic bacteria. Alteration in the composition of the gut microbiota is called dysbiosis. Dysbiosis redisposes to inflammatory bowel diseases such as ulcerative colitis, Crohn disease and indeterminate colitis. Methods: The purpose of this literature review is to elucidate the influence of diet on the composition of the gastrointestinal microbiota in the healthy gut and the role of diet in the development of dysbiosis. Conclusion: The "Western diet", in particular a low - fiber high fat/high carbohydrate diet is one factor that can lead to severe dysbiosis. In contrast, "mediterranean" and vegetarian diets that includes abundant fruits, vegetables, olive oil and oily fish are known for their anti-inflammatory effects and could prevent dysbiosis and subsequent inflammatory bowel disease.