RT Journal Article
SR Electronic
A1 Sleha, Radek
A1 Mosio, Petra
A1 Vydrzalova, Marketa
A1 Jantovska, Alexandra
A1 Bostikova, Vanda
A1 Mazurova, Jaroslava
T1 In vitro antimicrobial activities of cinnamon bark oil, anethole, carvacrol, eugenol and guaiazulene against Mycoplasma hominis clinical isolates
JF Biomedical papers
YR 2014
VO 158
IS 2
SP 208
OP 211
DO 10.5507/bp.2012.083
UL https://biomed.papers.upol.cz/artkey/bio-201402-0008.php
AB Aims: The aim of this study was to evaluate the antimicrobial effects of five natural substances against 50 clinical isolates of Mycoplasma hominis.
Methods and Results: The in vitro activity of selected natural compounds, cinnamon bark oil, anethole, carvacrol, eugenol and guaiazulene, was investigated against 50 M. hominis isolates cultivated from cervical swabs by the broth dilution method. All showed valuable antimicrobial activity against the tested isolates. Oil from the bark of Cinnamomum zeylanicum (MBC<sub>90</sub> = 500 µg/mL) however was found to be the most effective. Carvacrol (MBC<sub>90</sub> = 600 µg/mL) and eugenol (MBC<sub>90</sub> = 1000 µg/mL) also possessed strong antimycoplasmal activity.
Conclusions: The results indicate that cinnamon bark oil, carvacrol and eugenol have strong antimycoplasmal activity and the potential for use as antimicrobial agents in the treatment of mycoplasmal infections.