Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2013, 157(1):1-4 | 10.5507/bp.2013.023
Background: Marfan syndrome (MFS) is the most common inherited disorder of connective tissue affecting multiple organ systems. The most life-threatening and life-shortening complication is aortic dissection. Without surgery, life expectancy of MFS patients is reduced to approximately 32 years. Early identification and appropriate multidisciplinary medical cooperation is essential.
Conclusion: Proper follow up, therapy and timely surgical repair lead to an almost normal lifespan in affected individuals.
Received: March 6, 2013; Accepted: March 22, 2013; Prepublished online: March 25, 2013; Published: March 1, 2013